Search results for "virus populations"

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Identification of Replicator Mutator models

2006

The complexity of biology literally calls for quantitative tools in order to support and validate biologists intuition and traditional qualitative descriptions. In this paper, the Replicator-Mutator models for Evolutionary Dynamics are validated/invalidated in a worst-case deterministic setting. These models analyze the DNA and RNA evolution or describe the population dynamics of viruses and bacteria. We identify the Fitness and the Replication Probability parameters of a genetic sequences, subject to a set of stringent constraints to have physical meaning and to guarantee positiveness. The conditional central estimate is determined in order to validate/invalidate the model. The effectivene…

education.field_of_studyTheoretical computer sciencePopulationGenomicsPositive systemsBioinformaticsSet (abstract data type)Identification (information)virus populationsModels of DNA evolutionReplication (statistics)VirusesRNA VirusesEvolutionary dynamicseducationBiomedical systems; Evolutionary dynamics; Nonlinear systems; Positive systems; Uncertain dynamical systems;
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